Correlation of retinal nerve fiber layer measured by scanning laser polarimeter to visual field in ischemic optic neuropathy.

نویسندگان

  • Helen V Danesh-Meyer
  • Stuart C Carroll
  • Judy Y F Ku
  • John Hsiang
  • Brent Gaskin
  • Greg G Gamble
  • Peter J Savino
چکیده

OBJECTIVE To evaluate the relationship between retinal nerve fiber layer (RNFL) measurement with scanning laser polarimetry (SLP) and standard automated perimetry (SAP) in nonarteritic anterior ischemic optic neuropathy (NAION). METHODS In this prospective observational case series, all subjects (28 eyes with NAION) underwent SAP and SLP. The RNFL retardation measurements and visual field test points were grouped into 6 corresponding sectors. The contralateral uninvolved eye was used as control. The relationship between RNFL retardation and SAP was evaluated with the Spearman nonparametric technique and linear regression analysis. The main outcome measure was correlation of SLP RNFL parameters and SAP. RESULTS Global and sectoral SLP parameters showed a significant difference in affected eyes compared with controls. The strongest correlations were seen between mean deviation and number (r = -0.524; P = .004), ellipse modulation (r = 0.5026; P = .006), and maximum modulation (r = 0.526; P = .004). Superior sectoral visual field indexes showed a strong correlation with inferior RNFL changes (r = 0.522; P<.008). Linear regression confirmed a strong relationship between the superior sectoral visual field indexes and the inferior RNFL. CONCLUSION Scanning laser polarimetry was able to identify structural changes of the RNFL globally and in the inferior SLP sector with functional loss in NAION.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Axonal loss in a patient with anterior ischemic optic neuropathy as measured with scanning laser polarimetry.

PURPOSE To report Nerve Fiber Analyzer (NFA/GDx; Laser Diagnostic Technologies, San Diego, California) measurements in a patient during the early phase of an anterior ischemic optic neuropathy. METHODS Case report. A 58-year old man with acute anterior ischemic optic neuropathy had repeated NFA/GDx scans of the nerve fiber layer adjacent to the optic nerve head of the involved eye, as well as...

متن کامل

Correlation between photopic negative response and retinal nerve fiber layer thickness and optic disc topography in glaucomatous eyes.

PURPOSE To investigate whether there is a significant correlation between the photopic negative response (PhNR) of the electroretinogram (ERG) and retinal nerve fiber layer thickness and optic disc topography in glaucomatous eyes. METHODS Ninety-nine eyes of 53 patients with open-angle glaucoma (OAG) and 30 eyes of 28 normal volunteers were studied. Photopic ERGs were elicited by red stimuli ...

متن کامل

A Practical Guide for Interpretation of Optical Coherence Tomography Retinal Nerve Fiber Layer Measurement

Structural damage in glaucoma often occurs before detectable loss in visual function.1-3 Accurate assessment of the optic disk and retinal nerve fiber layer (RNFL) morphology, however, is not always an easy task. Optical coherence tomograph (OCT), confocal scanning laser ophthalmoscope (CSLO) and scanning laser polarimeter (SLP) are the 3 commonly used imaging instruments for objective measurem...

متن کامل

Scanning laser polarimetry reveals status of RNFL integrity in eyes with optic nerve head swelling by OCT.

PURPOSE Optical coherence tomography (OCT) shows retinal nerve fiber layer (RNFL) thickening in optic nerve head (ONH) swelling, but does not provide information on acute axonal disruption. It was hypothesized that scanning laser polarimetry (SLP) compared with OCT might reveal the status of axon integrity and visual prognosis in acute RNFL swelling. METHODS Threshold perimetry, OCT, and SLP ...

متن کامل

Correlation between Retinal Nerve Fiber Layer Thickness Measured by GDx and Visual Field in Nonarteritic Anterior Ischemic Optic Neuropathy: A Comparison with the Contralateral Normal Eye

Purpose: To evaluate the correlations between visual field (VF) defects with retinal nerve fiber layer (RNFL) thickness in nonarteritic anterior ischemic optic neuropathy (NAION) eyes, compare different GDx parameters with the other healthy contralateral eyes, and calculate receiver operating characteristic (ROC) curve for the GDx parameters Methods: Eighteen patients with unilateral NAION from...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:
  • Archives of ophthalmology

دوره 124 12  شماره 

صفحات  -

تاریخ انتشار 2006